Sedentary lifestyle linked to advanced biological aging

Sedentary lifestyle linked to advanced biological aging

A recent study by researchers at the University of San Diego investigated the impact of a sedentary lifestyle on cell age in elderly women and found that those who exercised the least had biologically ‘older’ cells than the more active participants. The findings were published in the February 2017 issue of the American Journal of Epidemiology.

The study, the first of its kind, investigated the link between sedentary time, exercise and telomere length in elderly women.


Telomeres are the structures at the ends of human chromosomes. Often likened to shoelace caps, they protect the ends of the chromosomes from damage or fusing with the ends of other chromosomes. As we age, our chromosomes divide to create new cells to ensure the optimized functioning of our bodies. Each time our chromosomes divide, the telomeres become a little shorter; eventually, when they become too short, the chromosomes can no longer divide, thereby preventing the creation of new cells. Telomere shortening has, therefore, been linked to many age-related diseases, such as cancer, heart disease and diabetes and research suggests that preventing the deterioration or even extending the length of telomeres can help fend-off these diseases and keep individuals physiologically ‘younger’ for longer.

The link between telomeres, exercise and biological age

In the study, researchers evaluated the link between leukocyte telomere length (LTL) and sedentary time in 1,481 white or African-American women, with an average age of 79 years.

Sedentary time was assessed using both self-reporting and an accelerometer. Participants filled in questionnaires and had their movements tracked by an accelerometer that they wore for 7 days in a row.

Researchers investigated the level of daily physical activity each participant engaged in as well as the association between LTL and sedentary time using multiple linear regression models. Lifestyle and health-related variables were also taken into account.

What they discovered was women who exercised for under 40 minutes and were sedentary for more than 10 hours each day had biologically ‘older’ cells than women who were less sedentary and exercised more. Alarmingly, low physical activity was attributed to an 8-year biological age gap between those who exercised and those who did not.

Increasing telomere length

While early research seems to suggest that individuals could increase the length of their telomeres by making lifestyle changes and exercising more, further studies are required to provide greater support to these findings.

However, 1Truth Serum with TAM-818 has been clinically proven to ‘switch on’ the telomerase enzyme in our bodies, which is responsible for preventing the deterioration of telomeres and can even increase their length, effectively increasing the lifespan of our chromosomes.

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